





The Zebra ZT421 keeps critical labeling operations moving with durable metal construction, wide-format 6-inch output and an intuitive 4.3-inch color touch display. Choose 203 or 300 dpi and the connectivity or media-handling configuration that fits the workflow.
Field-installable wireless, RFID and media-handling options let the printer evolve with changing requirements, while Zebra DNA for Printers tools simplify integration, security and remote management.
See the ZT421 industrial printer, touch interface and serviceable design.
Media, ribbon, cables, power cords and optional accessories are sold separately unless the selected option explicitly states they are included.
Standard Ethernet, serial, USB, dual USB Host and Bluetooth support common industrial connections. Optional Wi-Fi 6 and Bluetooth 5.3 add faster, more reliable wireless operation on modern networks.
Select tear, cutter, peel, liner take-up or full-rewind handling. ZT421 configurations support 203 or high-detail 300 dpi printing.
The 4.3-inch touch display presents printer status, settings and guided alerts in a familiar interface, while bi-colored LEDs provide quick status visibility.
A side-loading supply path, enlarged viewing window and bi-fold cover simplify replenishment and help the printer fit into constrained work areas.
Zebra DNA tools, powered by Link-OS, support setup, integration, remote configuration, troubleshooting and security across distributed printer fleets.
Optional internal communication and applicator-interface cards support evolving automation requirements without replacing the base printer.
Fast output, 256 MB SDRAM and 512 MB Flash help keep demanding print jobs moving, while adjustable transmissive and reflective sensors support varied label stocks.
A metal frame, metal media cover and serviceable design are built for sustained use in manufacturing, warehouse and distribution environments.

Match the selected print method, media width, roll and core size, sensing method and ribbon to the job. Use the POSGuys Label Selector Tool or contact us for help selecting supplies for a ZT421 configuration.
ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Bluetooth 4.1
DPI:
203
Interface:
Serial, USB, Ethernet, Bluetooth
Cutter Option:
Tear Bar
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.2
DPI:
203
Interface:
Serial, USB, Ethernet, Bluetooth
Cutter Option:
Tear Bar
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, WiFi
DPI:
203
Interface:
Serial, USB, Ethernet, Bluetooth, WiFi
Cutter Option:
Tear Bar
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Cutter w/ Catch Tray
DPI:
203
Cutter Option:
Cutter w/ Catch Tray
Interface:
Serial, USB, Ethernet, Bluetooth
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel w/ Full Rewind
DPI:
203
Cutter Option:
Peel w/ Full Rewind
Interface:
Serial, USB, Ethernet, Bluetooth
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, US Cord, Serial, USB, Ethernet, Bluetooth 4.1
DPI:
300
Interface:
Serial, USB, Ethernet, Bluetooth
Cutter Option:
Tear Bar
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel
DPI:
300
Cutter Option:
Peeler
Interface:
Serial, USB, Ethernet, Bluetooth
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Cutter w/ Catch Tray
DPI:
300
Cutter Option:
Cutter w/ Catch Tray
Interface:
Serial, USB, Ethernet, Bluetooth
Print Method:
Thermal Transfer
ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel w/ Full Rewind
DPI:
300
Cutter Option:
Peel w/ Full Rewind
Interface:
Serial, USB, Ethernet, Bluetooth
Print Method:
Thermal Transfer
USB Interface Cable, 6FT (A to B)
15FT USB Cable M-A TO M-B XI, 105SL, Z SER
203 to 300 DPI Conversion Kit for Zebra ZT421, ZT421R, and ZT420 Printers.
300 to 203 DPI Conversion Kit for Zebra ZT421, ZT421R, and ZT420 Printers.
ZT411, ZT421, Kit, Internal Print Server IPv4,
Parallel Port Interface Card on Zebra ZT411, ZT421, ZT410, and ZT420 Printers
ZT421, Kit, Platen Roller,
Replacement 203dpi Printhead for ZT421. Please Note: This product is non-returnable.
Replacement 300dpi Printhead for ZT421. Please Note: This product is non-returnable.
ZT421, Kit, RFID Module USA and Canada
Cable, KIT, USB Interface Cable, 10FT (A to B)
Zebranet Wireless Card. 802.11ac, BT4.0. USA and Canada. For all ZT111, ZT211, ZT231, ZT411/ZT421, ZT510, ZT600 Series printers, only ZT410/ZT420 printers with firmware V75.20.14Z or later. (BT4.2 unavailable on ZT111, ZT211, ZT231)
Antenna, Magnetic Mount for Internal Wireless Plus Antenna (Antenna not included)
Peeler (Dispenser) Upgrade Module for Zebra ZT421 / ZT421R Printer.
PS105-Z, SEH External IPv6 Print Server
Keyboard Display Unit (ZKDU), For all EPL and ZPL Printers, 62-Key QW
Zebra OneCare Essential 3-Year Comprehensive Warranty. For ZT421 and ZT421R Printers. Purchased within 30 days of Device.
Zebra OneCare Essential 5-Year Comprehensive Warranty. For ZT421 and ZT421R Printers. Purchased within 30 days of Device.