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Zebra ZT421

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A new level of performance, versatility and ease of use for 6-inch industrial printing.

The Zebra ZT421 keeps critical labeling operations moving with durable metal construction, wide-format 6-inch output and an intuitive 4.3-inch color touch display. Choose 203 or 300 dpi and the connectivity or media-handling configuration that fits the workflow.

Field-installable wireless, RFID and media-handling options let the printer evolve with changing requirements, while Zebra DNA for Printers tools simplify integration, security and remote management.

See the ZT421 industrial printer, touch interface and serviceable design.

Key Specifications

  • Print method: Thermal transfer and direct thermal
  • Resolution: 203 dpi; optional 300 dpi
  • Maximum print width: 6.6 in. / 168 mm
  • Print speed: Up to 12 ips / 305 mm per second
  • Media and ribbon handling: 1.00–4.50 in. media for tear/cutter or up to 4.25 in. for peel/rewind; 8 in. roll OD; 450 m ribbon
  • Connectivity: USB 2.0, RS-232 serial, 10/100 Ethernet, Bluetooth 4.2 and dual USB Host; optional Wi-Fi 6/Bluetooth 5.3 and interface cards
  • Duty / application fit: Industrial labeling in manufacturing, transportation and logistics, distribution, retail and healthcare operations
  • Dimensions and weight: Base model 19.5 × 10.6 × 12.75 in., 36 lb; full-rewind configurations are larger and heavier
  • Warranty: Zebra limited warranty; confirm current regional terms for the selected configuration

In the Box

  • Zebra ZT421 industrial printer in the selected configuration
  • Installed communication and media-handling hardware only when specified by the selected option

Media, ribbon, cables, power cords and optional accessories are sold separately unless the selected option explicitly states they are included.

Versatile to Meet Your Evolving Needs

Configure Your Way

Standard Ethernet, serial, USB, dual USB Host and Bluetooth support common industrial connections. Optional Wi-Fi 6 and Bluetooth 5.3 add faster, more reliable wireless operation on modern networks.

Handle More Media and Applications

Select tear, cutter, peel, liner take-up or full-rewind handling. ZT421 configurations support 203 or high-detail 300 dpi printing.

Effortless to Integrate and Operate

Large Color Touch Display

The 4.3-inch touch display presents printer status, settings and guided alerts in a familiar interface, while bi-colored LEDs provide quick status visibility.

Easy Media and Ribbon Loading

A side-loading supply path, enlarged viewing window and bi-fold cover simplify replenishment and help the printer fit into constrained work areas.

Easy to Manage

Zebra DNA for Printers

Zebra DNA tools, powered by Link-OS, support setup, integration, remote configuration, troubleshooting and security across distributed printer fleets.

Connect to Industrial Networks

Optional internal communication and applicator-interface cards support evolving automation requirements without replacing the base printer.

Performance You Can Count On

Maximum Throughput and Productivity

Fast output, 256 MB SDRAM and 512 MB Flash help keep demanding print jobs moving, while adjustable transmissive and reflective sensors support varied label stocks.

Rugged Industrial Durability

A metal frame, metal media cover and serviceable design are built for sustained use in manufacturing, warehouse and distribution environments.

Zebra-compatible barcode labels and ribbon

Looking for Compatible Labels or Ribbon?

Match the selected print method, media width, roll and core size, sensing method and ribbon to the job. Use the POSGuys Label Selector Tool or contact us for help selecting supplies for a ZT421 configuration.

Dimensions (L x W x H)
19.5 in. L x 13.25 in. W x 12.75 in. H 495 mm L x 336 mm W x 324 mm H
Weight
40 lbs./18.14 kg
Resolution
203 dpi/8 dots per mm 300 dpi/12 dots per mm (optional)
Memory
256 MB SDRAM memory 512 MB on-board linear Flash memory
Maximum Print Width
6.6 in./168 mm
Maximum Print Speed
12 ips/305 mm per second
Maximum Print Length
• 203 dpi: 102 in./2591 mm • 300 dpi: 45 in./1143 mm
Media Width
• 2.00 in./51 mm to 7.0 in./178 mm tear/cutter • 2.00 in./51 mm to 6.75 in./171 mm peel/rewind
Media Roll Diameter
8.0 in./203 mm O.D. on a 3 in./76 mm I.D. core
Media Thickness
0.0023 in./0.058 mm to 0.010 in./0.25 mm
Ribbon Length
1,476 ft./450 m
Ribbon Width
2.00 in./51 mm to 6.85 in./174 mm
Ribbon Core
1.0 in./25 mm I.D.
Operating Temperature
Thermal transfer: 40º F to 104º F/5º C to 40º C Direct thermal: 32º F to 104º F/0º C to 40º C
Zebra Industrial Printer Accessories Guide
Download
ZT421 Quick Setup Guide
Download
ZT421 RFID Spec Sheet
Download
ZT421 Spec Sheet
Download

Shop ZT421 Models

ZT42162-T010000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Bluetooth 4.1

DPI:

203

Interface:

Serial, USB, Ethernet, Bluetooth

Cutter Option:

Tear Bar

Print Method:

Thermal Transfer

$2820.02

ZT42162-T01000GA

ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.2

DPI:

203

Interface:

Serial, USB, Ethernet, Bluetooth

Cutter Option:

Tear Bar

Print Method:

Thermal Transfer

$2820.02

ZT42162-T01A000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, WiFi

DPI:

203

Interface:

Serial, USB, Ethernet, Bluetooth, WiFi

Cutter Option:

Tear Bar

Print Method:

Thermal Transfer

$3266.21

ZT42162-T210000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Cutter w/ Catch Tray

DPI:

203

Cutter Option:

Cutter w/ Catch Tray

Interface:

Serial, USB, Ethernet, Bluetooth

Print Method:

Thermal Transfer

$3618.28

ZT42162-T410000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 203 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel w/ Full Rewind

DPI:

203

Cutter Option:

Peel w/ Full Rewind

Interface:

Serial, USB, Ethernet, Bluetooth

Print Method:

Thermal Transfer

$3350.74

ZT42163-T010000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, US Cord, Serial, USB, Ethernet, Bluetooth 4.1

DPI:

300

Interface:

Serial, USB, Ethernet, Bluetooth

Cutter Option:

Tear Bar

Print Method:

Thermal Transfer

$3262.73

ZT42163-T110000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel

DPI:

300

Cutter Option:

Peeler

Interface:

Serial, USB, Ethernet, Bluetooth

Print Method:

Thermal Transfer

$3507.61

ZT42163-T210000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Cutter w/ Catch Tray

DPI:

300

Cutter Option:

Cutter w/ Catch Tray

Interface:

Serial, USB, Ethernet, Bluetooth

Print Method:

Thermal Transfer

$4057.49

ZT42163-T410000Z

ZT421 Industrial Label Printer. Thermal Transfer. 6", 300 dpi, Serial, USB, Ethernet, Bluetooth 4.1, Peel w/ Full Rewind

DPI:

300

Cutter Option:

Peel w/ Full Rewind

Interface:

Serial, USB, Ethernet, Bluetooth

Print Method:

Thermal Transfer

$3791.70

Shop ZT421 Accessories

105850-006

USB Interface Cable, 6FT (A to B)

$22.80

37996

15FT USB Cable M-A TO M-B XI, 105SL, Z SER

$33.23

P1058930-025

203 to 300 DPI Conversion Kit for Zebra ZT421, ZT421R, and ZT420 Printers.

$1232.24

P1058930-026

300 to 203 DPI Conversion Kit for Zebra ZT421, ZT421R, and ZT420 Printers.

$791.65

P1058930-074

ZT411, ZT421, Kit, Internal Print Server IPv4,

$486.58

P1058930-075

Parallel Port Interface Card on Zebra ZT411, ZT421, ZT410, and ZT420 Printers

$117.96

P1058930-081

ZT421, Kit, Platen Roller,

$117.62

P1058930-012

Replacement 203dpi Printhead for ZT421. Please Note: This product is non-returnable.

$791.65

P1058930-013

Replacement 300dpi Printhead for ZT421. Please Note: This product is non-returnable.

$1232.24

P1058930-500A

ZT421, Kit, RFID Module USA and Canada

$2547.08

G105850-007

Cable, KIT, USB Interface Cable, 10FT (A to B)

$32.17

P1083320-037A

Zebranet Wireless Card. 802.11ac, BT4.0. USA and Canada. For all ZT111, ZT211, ZT231, ZT411/ZT421, ZT510, ZT600 Series printers, only ZT410/ZT420 printers with firmware V75.20.14Z or later. (BT4.2 unavailable on ZT111, ZT211, ZT231)

$627.38

39518M

Antenna, Magnetic Mount for Internal Wireless Plus Antenna (Antenna not included)

$155.51

P1105147-020

Peeler (Dispenser) Upgrade Module for Zebra ZT421 / ZT421R Printer.

$370.00

P1000219

PS105-Z, SEH External IPv6 Print Server

$573.03

ZKDU-001-00

Keyboard Display Unit (ZKDU), For all EPL and ZPL Printers, 62-Key QW

$414.25

Z1AE-ZT421-3C0

Zebra OneCare Essential 3-Year Comprehensive Warranty. For ZT421 and ZT421R Printers. Purchased within 30 days of Device.

$577.67

Z1AE-ZT421-5C0

Zebra OneCare Essential 5-Year Comprehensive Warranty. For ZT421 and ZT421R Printers. Purchased within 30 days of Device.

$955.46