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Zebra ZD621R

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Premium 4-inch RFID label printing with adaptive encoding and enterprise-ready management.

The Zebra ZD621R combines premium 4-inch thermal-transfer printing with integrated UHF RFID encoding for asset, inventory and item-level identification. Choose 203 or 300 dpi and the connectivity, display or media-handling configuration that fits the workflow.

Adaptive Encoding Technology and the RE40 RFID Reader/Encoder simplify tag setup, while Link-OS, Zebra DNA tools and adaptable connectivity make the ZD621R easier to deploy, secure and maintain.

See the ZD621R RFID desktop printer and its encoding workflow.

Key Specifications

  • Print method: Thermal transfer with integrated UHF RFID encoding
  • Resolution: 203 dpi or optional 300 dpi
  • Maximum print width: 4.09 in. / 104 mm at 203 dpi; 4.27 in. / 108 mm at 300 dpi
  • Print speed: Up to 8 ips at 203 dpi or 6 ips at 300 dpi
  • Media and ribbon handling: 0.585–4.65 in. media; 5 in. roll OD; 74 m or 300 m ribbons; UHF EPC Gen 2 V2.1 and RAIN RFID
  • Connectivity: Ethernet, serial, USB 2.0, USB Host and BLE; optional Wi-Fi 5 or Wi-Fi 6 dual radio with Bluetooth
  • Duty / application fit: RFID asset, inventory, item-level and compliance labeling in retail, healthcare, manufacturing and logistics
  • Dimensions and weight: 10.5 × 8.0 × 7.5 in.; 5.5 lb
  • Warranty: Minimum 2-year Zebra warranty; regional terms apply

In the Box

  • Zebra ZD621R RFID printer in the selected configuration
  • AC power supply and regional power cord(s)
  • USB cable
  • Quick Start Guide and Regulatory Guide
  • 1-inch and 0.5-inch empty ribbon take-up cores plus two 300 m ribbon adapters

Media, ribbon and optional accessories are sold separately unless the selected option explicitly states they are included.

Your Future Printing Starts Here

Technology for Today, Innovation for Tomorrow

The ZD621R architecture handles more operations at once and supports emerging capabilities, while optional Wi-Fi 6 and Bluetooth 5.3 add WPA3 security, faster connections and improved roaming.

Encode RFID Without Complication

Adaptive Encoding Technology and the integrated RE40 reader/encoder simplify UHF tag calibration and support EPC Gen 2 V2.1 and RAIN RFID protocols.

Expect the Best

Premium Printing Performance

Fast 203 dpi output and optional 300 dpi detail support everyday desktop work, while the thermal-transfer media dancer helps maintain print quality across speeds.

Load Media Easily

Color-coded touch points, OpenACCESS media loading and replaceable media-handling options simplify changes and reduce training.

Simple to Setup, Easy to Maintain

Operate with Ease, Securely

Five status icons and three buttons show printer state at a glance; select configurations add a 4.3-inch full-color touch display with guided menus and troubleshooting.

Hassle-Free Integration

ZPL and EPL support, printer emulations and standard USB, Ethernet and serial connectivity ease fleet replacement. Optional dual radios add Wi-Fi and Bluetooth for mobile and network workflows.

Zebra DNA for Printers

Confident and Secure Printing

Zebra DNA tools, powered by Link-OS, simplify setup, remote management and troubleshooting while PrintSecure helps harden printer connections and block unauthorized access.

Zebra-compatible barcode labels and ribbon

Looking for Compatible Labels or Ribbon?

Match the selected print method, media width, roll and core size, sensing method and ribbon to the job. Use the POSGuys Label Selector Tool or contact us for help selecting supplies for a ZD621R configuration.

Dimensions
10.5 in. L x 8.0 in. W x 7.5 in. H / 267 mm L x 202 mm W x 192 mm H
Weight
5.5 lb./2.5 kg
Operating System
Link-OS® printer operating system
Resolution
203 dpi / 8 dots per mm; 300 dpi / 12 dots per mm optional
Memory
512 MB Flash; 256 MB SDRAM
Maximum Print Width
4.09 in./104 mm for 203 dpi; 4.27 in./108 mm for 300 dpi
Maximum Print Speed
8 ips / 203 mm per second at 203 dpi; 6 ips / 152 mm per second at 300 dpi
Media Sensors
Full width, moveable reflective/black mark sensor; multi-position transmissive/gap sensor
Firmware
ZPL II; EPL 2; XML; ZBI; PDF Direct
Regulatory
IEC 60950-1, IEC 62368-1, EN55022 Class B, EN55024, EN55035, EN61000-3-2, EN61000-3-3, FCC Class B, ICES-003, FCC 15.209; 15.247(d), IC RSS 247, EN 300 328, EN 301 893, EN 62311, cTUVus CE Marking, VCCI, C-Tick, S-Mark, CCC, CU, BSMI, KCC, SABS, IN-Metro, BIS, NOM
Environmental Compliance
RoHS Directive 2011/65/EU with Amendment 2015/863; REACH SVHC 1907/2006
Label Length
Minimum: 0.25 in. / 6.35 mm; Maximum: 39.0 in. / 991 mm
Media Width
0.585 in. / 15 mm to 4.65 in. / 118 mm
Media Roll Size
  • Maximum outer diameter: 5.00 in./127 mm
  • Core inner diameter: 0.5 in./12.7 mm and 1.0 in./25.4 mm standard, 1.5 in./38.1, 2.0 in./50.8 mm and 3.0 in./76.2 mm using optional adapters
  • Media Thickness
    0.003 in. / 0.08 mm minimum; 0.0075 in. / 0.19 mm maximum (tear-off mode only)
    Media Types
    Roll-fed or fan-fold, die cut or continuous with or without black mark, tag stock, continuous receipt paper, and wristbands
    Ribbon Outside Diameter
    2.6 in./66 mm (300 m); 1.34 in./34 mm (74 m)
    Ribbon Standard Length
    984 ft./300 m; 243 ft./74 m
    Ribbon Ratio
  • 1:4 ribbon to media (300 m)
  • 1:1 ribbon to media (74 m)
  • Ribbon Width
    1.33 in. / 33.8 mm to 4.3 in. / 109.2 mm
    Operating Temperature
    40° to 105° F/4.4° to 41° C
    Operating Humidity
    10% to 90% non-condensing
    Storage Humidity
    5% to 95% non-condensing
    Electrical
    Auto-detectable (PFC Compliant) 100-240VAC, 50-60Hz; ENERGY STAR certified; Energy Efficiency Level VI certified; optional 2750 mAh battery; Healthcare models include IEC60601-1 certified power supply
    Media Handling
    Dispenser/Peeler: label peel and present with label present sensor (factory installed or field installable) Cutter (factory or field installable)
    Communications
    Ethernet, USB 2.0, USB Host and RS-232 serial standard; optional dual-radio Wi-Fi 5 or Wi-Fi 6 with Bluetooth
    Keyboard Display Unit
    ZKDU keyboard display unit for stand-alone printing solution
    1D Barcodes
    Code 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A, UPC-E, EAN-8, EAN-13, UPC and EAN 2-or 5-digit extensions, Plessey, Postnet, Standard
    2D Barcodes
    Codablock, PDF417, Code 49, DataMatrix, MaxiCode, QR Code, MicroPDF, Aztec
    Fonts and Graphics
    16 resident expandable ZPL II bitmap fonts, two resident scalable ZPL fonts, five resident expandable EPL2 fonts, native open-type font support, Unicode compliant. China units include SimSun simplified Chinese font 64 MB user available non-volatile memory, 8 MB user available SDRAM
    ZD621R Spec Sheet
    Download
    ZD621R User Guide
    Download
    Zebra Desktop Printer Accessory Guide
    Download
    Zebra Setup Utility
    Download

    Shop ZD621R Models

    ZD6A142-301FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2224.80

    ZD6A143-301FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2287.97

    ZD6A142-301LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2449.70

    ZD6A143-301LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2560.04

    ZD6A142-311FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2216.21

    ZD6A142-311LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2488.27

    ZD6A142-321FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial

    $2396.15

    ZD6A142-321LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2673.24

    ZD6A143-311FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2326.53

    ZD6A143-311LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2598.60

    ZD6A143-321FR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial

    $2506.47

    ZD6A143-321LR1EZ

    ZD621R Thermal Transfer Barcode/RFID Printer, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, WiFi, BT4, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial, WiFi, Bluetooth

    $2783.54

    ZD6A143-301RR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2620.46

    ZD6A142-301RR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2507.74

    ZD6A142-31PFR2EZ

    CBE Thermal Transfer Printer (74/300M) ZD621, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, All Countries Except USA, Canada and Japan, Dispenser (Peeler), RFID - UHF, APAC Cord Bundle (EU, UK, AUS, JP), Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2264.18

    ZD6A143-301FR1GA

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL,TAA

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2337.51

    ZD6A142-301FR1GA

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL,TAA

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2229.80

    ZD6A142-301LR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ac, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2449.70

    ZD6A142-301LR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ac, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2449.70

    ZD6A142-311FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2216.21

    ZD6A142-321FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial

    $2396.15

    ZD6A142-321FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, Cutter, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    203

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial

    $2396.15

    ZD6A143-301FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2287.97

    ZD6A143-301FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2287.97

    ZD6A143-301LR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, 802.11ac, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2560.04

    ZD6A143-301LR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, 802.11ac, BT4, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    None

    Interface:

    USB, Ethernet, Serial

    $2560.04

    ZD6A143-311FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, Dispenser (Peeler), US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2326.53

    ZD6A143-311FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, Dispenser (Peeler), US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Dispenser (Peeler)

    Interface:

    USB, Ethernet, Serial

    $2326.53

    ZD6A143-321FR1EZ

    Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, USA/Canada, RFID - UHF, Cutter, US Cord, Swiss Font, EZPL

    DPI:

    300

    Add Ons:

    Cutter

    Interface:

    USB, Ethernet, Serial

    $2506.47

    Shop ZD621R Accessories

    P1080383-022

    Media Core Adaptors for 1.5", 2.0", 3.0" diameter cores. Set of 1 each. Compatible with Zebra ZD421 & ZD621 Printers.

    $60.32

    Z1AE-ZD6X1-3C0

    OneCare, Essential, Purchased within 30 days of Device, ZD621d, ZD621t, ZD621-RFID, 3 Years, Comprehensive

    $143.77

    P1079903-026

    Replacement Power Supply for Zebra Desktop Printer. 75W/24V with US & EU AC cords. Compatible with: ZD410, ZD411, ZD420, ZD421, ZD620, ZD621, ZD500.

    $200.83

    P1080383-234

    Attached Power Supply for use with Printer Power Carts. This removes the need for an external Power Supply. Attached Power Supply sits below the printer and is compatible with the Zebra ZD421 and ZD621. Must Purchase AC Power Cable (29928 or 29926) Separately.

    $328.44

    29928

    Universal AC Power Cord. 8ft (2.4m). 125.0 V / 13 A.

    $17.51

    29926

    Universal AC Power Cord. 4ft (1.6m). 125.0 V / 13 A.

    $15.12

    P1112640-233

    Peeler (Dispenser) Upgrade Module for Zebra ZD621T, ZD621R, and ZD421C Printers. NOT backwards compatible with the ZD420 or ZD620

    $53.62

    P1080383-603

    Battery for Zebra Desktop Printers. Compatible with ZD411, ZD421, ZD621, ZD410, ZD420, and ZD620. Requires Base Housing (P1080383-602 for ZD411/ZD611 / P1080383-600 for ZD421 & ZD621).

    $767.50

    P1080383-600

    Base Housing for Zebra Printer Battery. Compatible with Zebra ZD421, ZD621, ZD420, and ZD620. Purchase Battery (P1080383-603) Separately.

    $100.56